bookmark check_list close envelope home info pdf-color person process_train trash Merck MilliporeSigma aexaex_cex_stepapi_synthesismixerbioreactor_microcarrierbulk_apibulk_drug_substancecapsulecell_culturecell_culture_supplmentscell_harvestcentrifugationchromatographyclarificationclarification_2clarification_3clarification_centrifugationclarification_primaryclarification_primary_2clarification_triplecolumnconcentrationconjugation_w_carrier_proteincontainmentdownstreamfermentationfill_finishfillingfiltrationfiltration_activated_carbonfiltration_finalsterile_filtration final_sterile_filtration filtration_sterile_final filtration_sterile_final_2 virus_filtrationformulation_2harvestion_exchange_chromatographyknowledgelarge_moleculeliquid_cell_culture_medialyophilizationmedia_innoculum_prepmedia_inoculum_prepmixermixer_w_bagmixingmobius_flexreadymulti_step_precipitationpd_readypellicon_tffprefiltrationprefiltration_2purificationpurification_2small_moleculesteriletanktank_fattank_lowtransport_and_storageupstreamvent_and_bagvent_bioreactorvent_media_bioreactorvent_mixingvent_tankvirusvirus_2virus_removal final_formulation process cell line